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Posted Apr 14, 2026

Executive Director / Senior Director, Portfolio & Asset Strategy

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Location: Remote Compensation: $230–280K Base + Bonus + Equity Scientific Search has partnered with a well-funded clinical-stage oncology biotech developing next-generation antibody-drug conjugate (ADC) therapies targeting difficult-to-treat cancers. Our client is seeking an Executive Director / Senior Director of Portfolio & Asset Strategy to lead integrated strategy across multiple clinical-stage oncology assets. This role will serve as the strategic lead across the pipeline, working closely with senior leadership to shape development strategy, portfolio prioritization, and long-term asset value creation. This is a highly visible role ideal for a strategic biotech leader who enjoys working at the intersection of clinical development, corporate strategy, and business development in a collaborative, fast-paced environment. Responsibilities • Lead asset-level strategy across clinical-stage oncology programs including target product profiles, indication prioritization, biomarker strategy, clinical development planning, and commercial positioning • Translate complex clinical and scientific data into clear strategic recommendations for executive leadership and Board-level discussions • Partner closely with Clinical Development, R&D, Medical Affairs, Regulatory, and CMC to align development strategy across the organization • Integrate competitive intelligence, emerging clinical data, and market insights into ongoing portfolio strategy • Support business development initiatives, including diligence on potential in-licensing opportunities and new technologies • Contribute to partnering materials, investor communications, and strategic narratives supporting company growth • Engage external consultants, advisors, and key opinion leaders (KOLs) to inform strategy and development decisions Requirements • PhD, MD, PharmD, or MS/MBA with strong scientific and strategic background • 5–10+ years of experience in biopharma portfolio strategy, asset strategy, or new product planning • Experience in biopharma strategy consulting, investment banking, or equity research strongly preferred • Strong oncology background with experience supporting clinical-stage programs • Proven ability to operate effectively in small to mid-sized biotech environments • Experience working closely with executive leadership teams Preferred Experience • Experience with antibody-drug conjugates (ADCs), biologics, or targeted oncology therapies • Experience in lung cancer (NSCLC/SCLC) and/or gynecologic oncology • Background collaborating with Medical Affairs or translational science teams Why This Role • Highly visible strategic leadership role • Opportunity to shape strategy across multiple oncology assets • Work directly with executive leadership and influence portfolio-level decisions • Well-funded clinical-stage company with multiple catalysts ahead How To Apply We’d love to see your resume, but we don’t need it to have a conversation. Email [email protected] or message me directly if you’d like to learn more.
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