Posted: Jan 3, 2026
Legend Biotech is seeking Sr. Scientist, Vector Biology as part of the Research and Development team based in Philadelphia, PA. Key Responsibilities ? Hands-on work in developing, performing and optimizing lentiviral vector (LVV) production. ? Design and test various LVV payloads for developing chimeric antigen receptor (CAR) T cell therapy. ? Upstream and/or downstream process development using suspension cell culture with scale up in bioreactor ? Works independently in planning, performing, analyzing, reporting and presenting experimental data and future technology transfer ? Supports LVV production for internal research teams ? Prepare all technical reports needed in support of an exploratory project moving to process development. ? Interacts cross-functionally within the process development and analytical organizations, as well as with other departments (regulatory, quality, manufacturing, clinical, supply chain). Requirements ? BS degree with 4+ years; MS degree with 5+ years; PhD with minimum 3+ years in virology, molecular biology, cell & gene therapy or related field. ? Experience in lentiviral vector production and characterization ? Comfortable in a fast-paced biotech environment and able to adjust workload based upon priorities #Li-JK1 #Li-Onsite Apply Job!